The staff of the Centre for Evidence based Health Care actively participated in the recently held African Cochrane Indaba www.mrc.ac.za/conference/aci/index.htm at the Lagoon Beach Hotel in Cape Town. The Indaba commemorated the 15th Anniversary of the South African Cochrane Centre www.mrc.ac.za/cochrane as well as the 20th Anniversary of the Cochrane Collaboration www.cochrane.org. CEBHC staff facilitated and participated in workshops and presented posters. Charles Okwundu received the prize for the best poster presentation for his systematic review on ‘Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals’.